Moderator Profile

Executive Summary：
Dr. Chiung Chu CHEN is the associate Professor in the department of Neurology, Chang Gung Memorial Hospital (CGMH), Linko and department of Medicine in Chang Gung University. She is a movement disorders specialist and neurophysiologist and the Director of Movement Disorders Section in CGMH.
In 1998, she was involved with the setting up of the first DBS therapy center in Taiwan, a center she continued to lead now. Dr. Chen worked with Prof. Alim-Louis BENABID in Grenoble, France in 2004 and completed her PhD training under the supervision of Prof. Peter BROWN in Institute of Neurology, London, UK in 2008. She has used her training in movement disorders, deep brain stimulation (DBS) therapy and local field (LFPs) recording in patients with movement disorders to develop a unique translational program in basal ganglia electrophysiology and neuromodulation therapy in patients with movement disorders. Dr. Chen is leading interdisciplinary team including neurologists, IC design engineers and data scientist in CGMH, where they developed intraoperative and perioperative LFPs recording to help DBS targeting and post-operative programming to improve the efficacy of neuromodulation therapy for patients with movement disorders, such as Parkinson’s disease, dystonia and tremor. The team has defined important neuronal biomarkers predicting the long- term efficacy of DBS for PD patients and is using the computerized neuronal model to facilitate indivisualized therapy for patients underwent DBS.
In the past one decade, her research focused on the development of the closed-loop DBS. A novel paradigm that adaptively delivers stimulation subjective to the LFPs recorded from implanted DBS electrodes in patients. The final aim of her team is to investigate how the deranged basal ganglia neuronal activities contributing to movement and other neurological disorders in patients and identify the breakthrough in technology and neuromodulation therapy.